In this paper, we studied how display size affects human pointing performance given the same display field of view when using a mouse device. In total, four display sizes (10.6, 27, 46, 55 inches) and three display field of views (20°, 34° and 45°) were tested. Our findings show that given the same display field of view, mouse movement time significantly increases as display size increases; but there is no significant effect of display size on pointing accuracy. This research may contribute a new dimension to literature in describing human pointing performance on large displays. © 2013 Authors.